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Virology

  • 1)      What is the immunologic basis for the reduced vaccine effectiveness in Malawian children vaccinated with rotavirus vaccine?

    2)      Which rotavirus strains are circulating in Malawi and what is the impact of vaccine introduction on their evolution?

    3)      What is the safety and immunogenicity of the neonatal (RV3-BB) and sub-unit (P2-VP8*) rotavirus vaccines in Malawian infants?

    4)     Which arboviruses are circulating in Malawi and what is their burden of disease?