The Malawi-Liverpool-Wellcome (MLW) Programme (http://www.mlw.mw) is an internationally recognized centre for research and research training, funded by the Wellcome Trust. In collaboration with the Kamuzu University of Health Sciences (KUHeS). MLW would like to engage the services of a competent and dynamic individual to work in an exciting Research Programme at the MLW Research facility as it is expanding.
Post Doctoral Research Associate- Immunology – 1 post, based in Blantyre (initial 12 months contract with the possibility of renewal)
MLW and LSTM host a novel programme of Controlled Human Infection Model (CHIM) studies called Malawi Accelerated Research in Vaccines by Experimental and Laboratory Systems (MARVELS). Healthy volunteers and other selected subjects are deliberately infected with pathogens in a closely supervised manner to allow laboratory investigation to determine the pathogenesis of disease, surrogates of protection, effect of vaccines and mechanisms of other interventions. We have studied pneumococcal carriage, respiratory viral co-infection and plan other CHIM studies including salmonella and mycobacteria.
The programme requires an Immunologist at post-doctoral level to plan and run experiments to determine the mechanism of CHIM infection and response. This will require a broad knowledge of human immunology, experimental design and laboratory methods. Bioinformatic skills would be an advantage. The MARVELS Immunologist will also contribute to the research agenda and growth of the Lung Health group at MLW as well as the Clinical and Experimental Medicine, Infection Biology and other Themes. The post-holder will be expected to contribute to wider MLW collaborative activities including colleagues at KUHES.
• Design and implement immunological assays and experiments within the MARVELS programme.
• Perform data analyses and draft scientific manuscripts for publication.
• Contribute to the MLW research agenda and lead or contribute to research grant applications as principal or co-investigator or collaborator, including personal fellowships.
• Contribute to the line management of research assistants and fieldworkers within the MARVELS programme.
• Supervise internships and MSc-level candidates in Immunology and contribute to the scientific plans of student and intern projects.
• Contribute to the running and maintenance of the Immunology facility in MLW Laboratories and collaborator sites.
• Present work at national or international seminars, meetings and / or conferences.
• Assist with drafting or revising standard operating procedures for the Lung Health, MARVELS, Immunology or other relevant groups.
• Assist with writing and submission of ethical approval applications.
• Undertake any other reasonable administrative tasks as requested by the Lung Health group head.
Qualifications and Experience
- D. (or equivalent) degree in Human Immunology or closely related disciplines, ideally with a specialist interest in Infectious Diseases.
- At least 3 years’ experience of applying and / or researching human immunology (including during PhD).
- At least 3 years’ experience in study design and data analysis.
- Experience or knowledge of molecular-based methods in Infectious Diseases to detect pathogens and genotypes
- Knowledge of GCP requirements for human clinical research.
- Critical thinking skills
- Demonstrate a drive for continued self-learning and career development in research
- Demonstrate an active approach to enhancing productivity at work to meet agreed research milestones.
- Excellent communication skills (both written and oral) with the ability to communicate at all levels.
- Good working knowledge of Microsoft Office applications and statistical (e.g. R-programmes).
Remuneration and Benefits
MLW offers an attractive remuneration package which includes a competitive salary package commensurate with the position, a medical aid scheme, 24 hours insurance cover, pension scheme, gratuity benefits redeemable once every year, among others.
MLW also offers opportunities such as scholarships, upgrading and training opportunities to employees. These are based on successful job performance and other set criteria.
MLW recognizes its responsibility in safeguarding and protecting communities, research participants and patients. Please note that successful candidates will be requested to undergo a safeguarding check prior to appointment and at regular time points during employment.
Suitably qualified candidates should forward their applications with copies of relevant certificates, 3 contactable referees and a detailed CV to this email firstname.lastname@example.org
To arrive no later than the 16th June, 2022, only short-listed candidates will be acknowledged.