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Welcome to MLW

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We conduct internationally excellent research to benefit health and we train the next generation of researchers. In pursuit of this important mission, MLW is implementing two clinical research programmes focusing on preventing death and transmission of infections.

MLW is closely linked with the community and is an integral part of the University of Malawi's College of Medicine. These relationships provide a unique opportunity replicated in few centres in Africa to study major health issues spanning both community and hospital. Malawi provides a unique supportive environment, with government commitment to universal health coverage, strong engagement with research and willingness to innovate around evidence-based public health programmes. MLW surveillance and diagnostic platforms provide clinicians with early indicators of changes in the incidence of common and emerging diseases.

We study individual and community behaviour and bring this together with basic biology in order to plan appropriate interventions that improve health. Our translational pipeline, while providing an excellent academic environment, results in significant clinical trials and we transfer the findings to policy leading to improved health in Malawi and world-wide.

Most Recent Publications

Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii. Boinett CJ, Cain AK, Hawkey J, Do Hoang NT, Khanh NNT, Thanh DP, Dordel J, Campbell JI, Lan NPH, Mayho M, Langridge GC, Hadfield J, Chau NVV, Thwaites GE, Parkhill J, Thomson NR, Holt KE, Baker S. Microb Genom. 2019 Feb 5. doi: 10.1099/mgen.0.000246. [Epub ahead of print]

HIV is associated with endothelial activation despite ART, in a sub-Saharan African setting. Kamtchum-Tatuene J, Mwandumba H, Al-Bayati Z, Flatley J, Griffiths M, Solomon T, Benjamin L. Neurol Neuroimmunol Neuroinflamm. 2018 Dec 21;6(2):e531. doi: 10.1212/NXI.0000000000000531. eCollection 2019 Mar.

Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis. MacPherson P, Khundi M, Nliwasa M, Choko AT, Phiri VK, Webb EL, Dodd PJ, Cohen T, Harris R, Corbett EL.
BMC Med. 2019 Jan 29;17(1):21. doi: 10.1186/s12916-019-1260-6.

Pneumococcal colonization in healthy adult research participants in the conjugate vaccine era, United Kingdom, 2010-2017.
Adler H, Nikolaou E, Gould K, Hinds J, Collins AM, Connor V, Hales C, Hill H, Hyder-Wright AD, Zaidi SR, German EL, Gritzfeld JF, Mitsi E, Pojar S, Gordon SB, Roberts AP, Rylance J, Ferreira DM J Infect Dis. 2019 Jan 28. doi: 10.1093/infdis/jiz034. [Epub ahead of print]

Infrequent Transmission of Monovalent Human Rotavirus Vaccine Virus to Household Contacts of Vaccinated Infants in Malawi. Bennett A, Pollock L, Jere KC, Pitzer VE, Lopman B, Parashar U, Everett D, Heyderman RS, Bar-Zeev N, Cunliffe NA, Iturriza-Gomara M. J Infect Dis. 2019 Jan 24. doi: 10.1093/infdis/jiz002. [Epub ahead of print]

ChloS-HRM, a novel assay to identify chloramphenicol-susceptible Escherichia coli and Klebsiella pneumoniae in Malawi.
Williams CT, Musicha P, Feasey NA, Adams ER, Edwards T. J Antimicrob Chemother. 2019 Jan 25. doi: 10.1093/jac/dky563. [Epub ahead of print]