A new publication from the Malaria Genomic Epidemiology Network (MalariaGEN) in Nature Genetics, involving Prof Malcolm Molyneux and others from MLW, has assessed nearly 12,000 patients with severe malaria and over 17,000 controls were successfully genotyped to explore positive or negative host genetic associations with severe malaria.

Why do human falciparum malaria infections lead to such a variety of degrees of illness, ranging from no symptoms at all to life-threatening disease?